The frequency of eating affects the health of mice


Reducing the frequency of eating helps to improve the health of rodents and extend their life more than reducing the amount, while scientists ruled out the possibility of confirming the validity of these results at the level of humans as well, according to a recent study. The researchers, who analyzed groups of mice on different diets, concluded that those that were fed fewer calories in one daily meal lived longer than mice that ate the same number of calories in meals spread throughout the day. The study, whose results were published in the journal Nature Metabolism, showed that mice that ate only once a day also showed an improvement in their metabolism.
Study author Dudley Laming of the University of Wisconsin told AFP that scientists have known for nearly a century that limiting calories extends the life of rodents. But previous studies of calorie restriction in mice have involved unintended fasting, with mice usually feeding only once a day.
Laming’s team decided to see if timing between meals might play a role, and concluded that it wasn’t just the amount of food that mattered.
“Instead, calorie-restricted diets ensure that mice fast for most of the day, and imposing a fasting period (when we eat) is critical to the life and health benefits of calorie restriction,” he said. Laming’s team put the mice on different diets; The control group had unlimited access to regular food.
Two other groups were restricted in calories by 30 percent, one with access to reduced-calorie food throughout the day, and the other receiving 30 percent less than normal food in a single meal with a 21-hour fast.
The study showed that mice on a calorie-restricted diet with an interval of 21 hours between meals lived about half a year longer than mice that ate as much as they wanted at any time of the day.
On the other hand, mice with constant access to a reduced-calorie diet lived slightly shorter lives than the control group.


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