Scientists at Stanford University and North Carolina in the United States have developed a 3D-printed vaccine patch that is able to provide greater protection than typical vaccine doses, and the method is to apply the vaccine patch directly to the skin full of immune cells that the vaccine works to target.
The website of the American “Eurasia Review” magazine, quoting the study of scientists published in the journal “National Academy of Sciences”, stated that the immune response caused by the vaccine patch they created is 10 times more than the vaccine that is injected into the arm muscle with a needle strike.
A significant innovation is the three-dimensional microneedles lined up on a polymer patch, which are so short that they barely reach the skin to deliver the vaccine.
“By developing this technology, we hope to lay the groundwork for faster global development of vaccines at lower doses in a pain-free and worry-free way,” said lead study author and 3D-printing technology entrepreneur Joseph de Simone, a professor of transformational medicine and chemical engineering at Stanford University.
The vaccine patch can be used on its own. The results of the study showed that the vaccine patch generated a significant response to T cells and antigen-specific antibodies 50 times greater than the subcutaneous injection.
This immune response to the vaccine patch may result in dose avoidance, and the use of a smaller dose to generate an immune response similar to the vaccine with a needle and syringe.
While the mass vaccination process faces obstacles from cold storage of vaccines to the need for trained professionals who can give the vaccines, the scientists reported that the vaccine patch, which includes microscopic needles coated with the vaccine that dissolves in the skin, can be shipped without special treatment, and people can place the patch themselves. This may lead to higher vaccination rates.