Study: patients with sickle cell anemia are more likely to have severe cases of corona


A recent study showed that having a history of severe pain episodes and associated organ conditions increases the risk of severe COVID-19 disease, including hospitalization, in individuals with severe disease. Sickle cell anemia.

The study, published in the journal Blood Advances on the need for COVID-19 risk reduction and vaccination strategies for this medically at-risk population.

Sickle cell disease is the most common hereditary red blood cell disorder in the United States, affecting an estimated 100,000 people. According to a report by the site TIME NOW NEWSThe condition can cause severe pain, joint and organ damage, and stroke. These conditions predispose individuals with sickle cell anemia to worse outcomes with infections, including coronavirus.

Previous research has shown that patients with COVID-19 and sickle cell anemia are at greater risk of hospitalization than individuals without sickle cell anemia who develop infection..

The new study draws on data from Secure-SCD , an international registry that collects information about corona infection in individuals living with sickle cell anemia, including details on hospitalization, risk, management strategies, and complications.

The researchers evaluated 750 children and adults presented to the registry between March 2020 and March 2021. Half of the patients they studied were children aged 18 or younger, and half were adults with a mean age of 31, the researchers found. falciparum and those who previously had more than two acute pain conditions were 2.2 times more likely to be hospitalized with COVID-19 and more than 3 times more likely to have severe COVID-19.

“This study tells us that not all individuals with sickle cell disease are at equal levels of risk but that patients with a history of pain, as well as individuals with concurrent organic disease, need to be treated,” said study author Lana Mukalo of the Medical College of Wisconsin. They are more careful to avoid infection with corona than those who do not suffer from any comorbidities“.

Mukaloo also noted that after corona vaccines become available, clinicians and patients alike need to be aware of these risk factors when considering vaccination and that caregivers who provide care for individuals with sickle cell disease should recommend vaccination, especially for those with this disease. Comorbidities that put them at greater risk


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