One for inflammation and the other for AIDS.. two promising drugs to treat corona

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Despite the arrival of a number of vaccines to curb the outbreak of the Corona virus, which exhausted humanity more than a year ago, claiming more than 3 million lives around the world, the mysterious virus still continues to claim more lives and infect millions, especially since vaccines are not 100% effective.

Moreover, some people cannot receive vaccinations due to health problems, and new variants of the virus are being reported, highlighting the need now more than ever for effective antiviral therapies. Given this need, a team of researchers at the National Institute of Infectious Diseases in Japan, the British University of Oxford, and the American Indiana University launched a collaborative project, with the aim of finding a cure for Covid 19.

Remove the virus from the patient’s lungs in less than 4 to 9 days

In an exciting result, announced on June 4, in the latest issue of the journal “iScience”, researchers found two drugs that provide inhibitory efficacy for the emerging corona virus, which are “cepharanthen”, which is used to treat inflammation, and “nelfinavir”, which is approved to treat HIV infection. HIV/AIDS, according to Asharq Al-Awsat newspaper.

Cifaranthin prevented the virus from entering cells by preventing the virus from binding to the protein on the cell membrane, which it uses as a gateway. In contrast, nelfinavir prevented the virus from reproducing inside the cell by inhibiting the protein that the virus depends on for reproduction.

Given that these two drugs have distinct antiviral mechanisms, using them together can be especially effective for patients, with computational models predicting that the combined treatment with “cefaranthin – nelfinavir” can accelerate the removal of the virus from the patient’s lungs in less than 4 to 9 days. .

Not ready!

This dual therapy is not yet ready for use in healthcare systems, but the findings justify the need for further research into the clinical potential of cepharanthen-nelfinavir, and only then can we say with certainty that it is beneficial.

Given the ongoing nature of the epidemic and the ever-increasing number of deaths, the researchers stress that the development of the treatment “cefaranthin – nelfinavir” may provide clinicians and patients with a much-needed new option.

Treating a patient with corona - iStock

Treating a patient with corona – iStock

The Corona virus has killed more than 3.73 million people in the world since the World Health Organization office in China reported the emergence of the disease at the end of December 2019, according to a census conducted by Agence France-Presse based on official sources on Sunday.

More than 173 million people have been confirmed infected with the virus since its appearance, and the vast majority of those infected have recovered, although some continue to feel symptoms after weeks or even months.







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