Infection with COVID-19 does not provide permanent immunity against mutations of the virus


London – The immune response after infection with the Corona virus varies between individuals, and may not be sufficient to combat the “alpha” and “beta” variants of the Covid-19 virus, which confirms the importance of taking booster doses of Corona vaccines, according to what a new study revealed.

The World Health Organization has given new names to the novel coronavirus mutants, turning the “British mutant” into “alpha”, “South African” into “beta” and “Indian” into “delta”. What is the reason that called the international organization for this step?

The study found that people who were infected with corona secreted weak immune bodies, after six months of recovery from the virus, and failed to form antibodies against the “alpha” and “beta” variants.

The University of Oxford conducted the study, in cooperation with the universities of Liverpool, Sheffield, Newcastle and Birmingham, and the results that were reached indicate that whether infection with the virus is accompanied by symptoms or without symptoms, it does not necessarily protect people in the long term from infection from the new Corona variables of concern.

“Our study is one of the most comprehensive in uncovering the immune response in individuals who experienced symptoms or who did not have any symptoms of the virus,” said researcher Christina Dold of the University of Oxford. It is very important for everyone to get vaccinated, even if some have previously had COVID-19.”

“We found that individuals showed completely different immune responses from each other after infection with Covid-19, with no evidence of immune memory in some people from the two groups with or without symptoms six months after infection or even earlier,” Dold added.

The study examined how the immune system responded to Covid-19 in 78 health care workers who had symptoms or who had no symptoms of the virus, and eight other patients who had severe symptoms were also included.

Blood samples were taken monthly from the first month to the sixth month after infection to examine the different elements of the immune response.

The team found an early immune signature, detectable one month after infection, associated with both cellular immunity and antibodies, which predicted the strength of the immune response measured six months after infection.

This is the first time such fingerprinting has been found and has greatly improved scientists’ understanding of how enduring immunity develops. While the majority of people who experienced symptoms achieved measurable immune responses within six months after infection, a significant proportion of them (26 percent) did not achieve this.

The researchers who supervised the study said that the vast majority of people who contracted the virus without symptoms (92 percent) did not show a measurable immune response within six months after infection.


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