4 answers to the tough questions of the new Johnson & Johnson vaccine

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Food and Drug Administration Its approval of the emergency use of the vaccine for adults aged eighteen and on after its committee of external experts unanimously approved it on Friday.

In response to many questions, a scientist answered Viruses At Rochester Institute of Technology, Maureen Ferrand, on a number of related questions With a vaccine "Johnson & Johnson"According to the transfer site "Economic Times":

How does the vaccine work?

It is called a vaccine "Johnson & Johnson" What is known as"Virus vectors"Where the team that developed the vaccination took an attenuated virus "Glandular" He has 52 different serotypes, and they replace a small portion of his genetic instructions with genes Corona VirusAny protein "SARS-CoV-2".

Then the cells read the genetic instructions needed to make a protein "Spike", For the immune system to notice the protein "Intruder", And it generates antibodies, which protect the person in the event that he is exposed to the virus in the future.

The adenovirus vectors are completely safe, and the most suitable for genetic modification, as the vector is a virus from which the reproductive gene has been removed, and therefore it does not represent a threat to the body in terms of infection.

How effective is it?

In global trials of the vaccine, which included 44,000 individuals, it was found that the vaccine is 66 percent effective in preventing moderate and severe infection with the Coronavirus four weeks after vaccination, and by 100 percent in preventing hospitalization and death from the disease.

How is it different from other vaccines?

Vaccine depends "Johnson & Johnson" On vectors from Viruses Adenomyosis, while adopting a vaccine "Moderna" And"Pfizer" Messaging RNA technology, meaning the use of genetic instructions from the Coronavirus to tell a person’s cells to make a protein "Spike"Without using another virus as a vector.

Also vaccination is done with a vaccine "Moderna" And"Pfizer" In the form of two doses, while the vaccination comes "Johnson & Johnson" In one dose.

The vaccine can be shipped and stored "Johnson & Johnson" In regular coolers, which makes it easier to distribute compared to my vaccine "Pfizer" And"Moderna" To be kept in freezing point.

Should one vaccine be preferred over another?

Medical studies and research indicate the safety of all vaccines provided to prevent the emerging corona virus, so experts recommend that individuals obtain any vaccine available to them, due to the effectiveness of different types of vaccination in the face of Covid-19.

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And announced Food and Drug Administration Its approval of the emergency use of the vaccine for adults aged eighteen and on after its committee of external experts unanimously approved it on Friday.

In response to many questions, a scientist answered Viruses At Rochester Institute of Technology, Maureen Ferrand, on a number of related questions Johnson & Johnson vaccineAccording to the “Economic Times” website:

How does the vaccine work?

The Johnson & Johnson vaccine is called what is known as a “virus vector.” Corona VirusThat is, the SARS-Cove-2 protein.

Then the cells read the genetic instructions needed to make the “spike” protein, so that the immune system notices the “intruder” protein, and generates antibodies that protect the person in case he is exposed to the virus in the future.

The adenovirus vectors are completely safe, and the most suitable for genetic modification, as the vector is a virus from which the reproductive gene has been removed, and therefore it does not represent a threat to the body in terms of infection.

How effective is it?

In global trials of the vaccine, which included 44,000 individuals, it was found that the vaccine is 66 percent effective in preventing moderate and severe infection with the Coronavirus four weeks after vaccination, and by 100 percent in preventing hospitalization and death from the disease.

How is it different from other vaccines?

The Johnson & Johnson vaccine is dependent on vectors from Viruses Adenovirus, while the “Moderna” and “Pfizer” vaccines adopt messenger RNA technology, that is, the use of genetic instructions from the Corona virus to tell a person’s cells to make a “spike” protein, without using another virus as a vector.

The vaccination of “Moderna” and “Pfizer” vaccines is also given in two doses, while the “Johnson & Johnson” vaccine comes in one dose.

“Johnson & Johnson” vaccine can be shipped and stored in regular refrigerators, which facilitates distribution compared to my vaccinesPfizer” And”ModernaTo be kept in freezing point.

Should one vaccine be preferred over another?

Medical studies and research indicate the safety of all vaccines provided to prevent the emerging corona virus, so experts recommend that individuals obtain any vaccine available to them, due to the effectiveness of different types of vaccination in the face of Covid-19.







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