Study: Pfizer vaccine is effective for preventing a mutated strain of Coronavirus


The preliminary results of two studies published on Wednesday showed that the Pfizer / Bionic Alliance vaccine against the emerging corona virus appears to be effective against the mutated version that was discovered in Britain and is causing world concern due to its high ability to transmit.
And an international team of researchers at British and Dutch universities said in one of the two studies that other experts have not yet verified their results, that “our results show that most of the responses to the vaccine are supposed to be effective against version B1 1 7.”
To assess the effectiveness of the vaccine, the researchers placed in the laboratory the English version of the virus in front of the plasma of 36 patients who had recovered from Covid-19 and had severe or moderate symptoms.
It was found that “the majority of samples” were able to “inactivate” the mutated virus, although the “ability” of inactivation was low in three of the samples studied.
In a separate initial study, a team of researchers from Pfizer / Biontec reached similar results, by comparing the effect of the plasma of 16 volunteers in their clinical trials on the English mutant and the original virus discovered in Wuhan.
They concluded that the ability to “deactivate” the virus is similar in both cases, and judged from this that it was “unlikely” that the English mutated version would be able to “evade the protection” provided by their vaccine. If that happens, experts point to the “flexibility” of the messenger RNA technology that allows the vaccine to be modified to adapt it to a new version of the virus.
In a study published online in early January, researchers at Pfizer / Biontec considered that the vaccine appears to be effective against a “major mutation” that occurs in the virus common to the British, South African and Brazilian versions.
This mutation called “N501Y” occurs in the spine of the virus, which is a protein protrusion on the viral envelope that allows it to bind to human cells to enter them, and then it plays a major role in transmitting infection.
But scientists are especially concerned about the effectiveness of the vaccine against another mutation called “E484Ki”, which can be found in the South African and Brazilian versions, not in the English.
In this context, it is “important to continue monitoring the mutated copies and assessing their effect on the neutralization process (infection) in laboratory studies,” according to the authors of the first study.


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