Lipocalin 2 may help treat obesity


A new study found that the hormone lipocalin 2, found naturally in humans and mice, can treat obesity.

Researchers said that the hormone LCN2, which is secreted by bone cells and is found naturally in mice and humans, has been shown during experiments to make mice feel full after eating a meal.”LCN2 acts as a signal of satiety after a meal, which causes mice to limit their food intake, and it does so by affecting the hypothalamus area inside the brain,” said study lead author Perestra Larina Petropolo, in a press release.

“We wanted to see if LCN2 had similar effects in humans, and whether a dose of it was able to cross the blood-brain barrier,” she added.

Researchers found that LCN2 was also linked to decreased hunger after a meal, according to the study, published Tuesday in the journal “eLife” medical.

The researchers conducted the study by analyzing the amount of LCN2 in the blood of study participants before and after a meal. They found an increase in LCN2 levels in people of normal weight coincided with feeling full after a meal, but levels decreased in people who were overweight or obese.

The researchers said that this indicates that low levels of the hormone LCN2 may contribute to an increase in obesity and that its presence in a balanced manner in the body may have the ability to curb the feeling of hunger, thus reducing food consumption and treating obesity, according to what the “UPI” website reported. .


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