After human trials … 4 dangerous facts about the Russian vaccine against Corona

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Does it give long immunity? .. “The Lancet” report answers

During the past hours, the “Lancet” medical journal published the results of the first and second phase of human trials of the Russian “Sputnik” vaccine; What helped identify a dangerous set of facts.

On August 11, the Al-Hurra channel said: Russian President Vladimir Putin announced that Moscow had succeeded in developing the first vaccine for the Corona virus, and that it had been approved for use.

The vaccine has been attacked and criticized strongly by scientists in various parts of the world, due to the fact that the vaccine did not pass all the required tests and was hasty to announce it. Human experiments were not completed until only two months before it was announced.

The report of the medical journal “The Lancet” revealed four facts, which the report focused on extracting from the results: Which:

* The idea of ​​a vaccine
The magazine confirmed that the vaccine depends on its idea on adenoviruses, which are the common cold viruses called Ad5 and Ad26, after they have become safe and unable to grow in the body, and which work to identify the body’s cells with the genetic code for the Corona virus proteins, called “spike protein.”

She added that when people are injected with these modified adenoviruses, the immune system is stimulated to recognize the Corona virus and respond to it, but it is not clear if the immunity lasts for years.

The magazine pointed out that the idea of ​​the vaccine used by the Russians is not new, and some other Corona vaccines that researchers are working on are used, including the Oxford University vaccine and the Ad26 vaccine developed by Johnson & Johnson.

Is it safe?
The Lancet stated that all adenovirus-based vaccines are safe, even at high doses; So Sputnik vaccine is safe for people between the ages of 18 – 60 years, but she wondered: Does it really protect against the Corona virus?

Does it give long immunity?
Russian experiments showed that the vaccine stimulates high levels of antibodies that can stick to the communication protein in the emerging virus, but the most important measure is the level of antibodies that work, and can the antibodies prevent or neutralize the virus? Which is not answered by the results.

The magazine indicated that the levels of antibodies are very low in this study, compared to trials of other published vaccines. So are the responses of T cells (the other arm of the immune system to fight the virus).

She emphasized that in the absence of international reference standards, it is not possible to know whether this vaccine is better or worse compared to the others.

The magazine added that it is difficult to determine if this level of neutralization for the virus provided by the vaccine is sufficient to protect against infection, and it is also difficult to determine how long these antibodies remain in the blood, as experiments show results after only one month.

Is it ready for general use?
The magazine stated that despite the positive results of a small trial of the first phase of the Sputnik vaccine, it must be tested on a much larger group of people before it is used and given to people.

And she stressed the need to test all vaccines on large numbers of people, of different ages and races, in the third phase of clinical trials, adding that the third phase trials are necessary to gain a high level of confidence that the vaccine protects against infection, and it also helps to get rid of side effects Rare that may not appear in a small group of healthy volunteers.

After human trials … 4 dangerous facts about the Russian vaccine against Corona

Previously

During the past hours, the “Lancet” medical journal published the results of the first and second phase of human trials of the Russian “Sputnik” vaccine; What helped identify a dangerous set of facts.

On August 11, the Al-Hurra channel said: Russian President Vladimir Putin announced that Moscow had succeeded in developing the first vaccine for the Corona virus, and that it had been approved for use.

The vaccine has been attacked and criticized strongly by scientists in various parts of the world, due to the fact that the vaccine did not pass all the required tests and was hasty to announce it. Human experiments were not completed until only two months before it was announced.

The report of the medical journal “The Lancet” revealed four facts, which the report focused on extracting from the results: Which:

* The idea of ​​a vaccine
The magazine confirmed that the vaccine depends on its idea on adenoviruses, which are the common cold viruses called Ad5 and Ad26, after they have become safe and unable to grow in the body, and which work to identify the body’s cells with the genetic code for the Corona virus proteins, called “spike protein.”

She added that when people are injected with these modified adenoviruses, the immune system is stimulated to recognize the Corona virus and respond to it, but it is not clear if the immunity lasts for years.

The magazine pointed out that the idea of ​​the vaccine used by the Russians is not new, and some other Corona vaccines that researchers are working on are used, including the Oxford University vaccine and the Ad26 vaccine developed by Johnson & Johnson.

Is it safe?
The Lancet stated that all adenovirus-based vaccines are safe, even at high doses; So Sputnik vaccine is safe for people between the ages of 18 – 60 years, but she wondered: Does it really protect against the Corona virus?

Does it give long immunity?
Russian experiments showed that the vaccine stimulates high levels of antibodies that can stick to the communication protein in the emerging virus, but the most important measure is the level of antibodies that work, and can the antibodies prevent or neutralize the virus? Which is not answered by the results.

The magazine indicated that the levels of antibodies are very low in this study, compared to trials of other published vaccines. So are the responses of T cells (the other arm of the immune system to fight the virus).

She emphasized that in the absence of international reference standards, it is not possible to know whether this vaccine is better or worse compared to the others.

The magazine added that it is difficult to determine if this level of neutralization for the virus provided by the vaccine is sufficient to protect against infection, and it is also difficult to determine how long these antibodies remain in the blood, as experiments show results after only one month.

Is it ready for general use?
The magazine stated that despite the positive results of a small trial of the first phase of the Sputnik vaccine, it must be tested on a much larger group of people before it is used and given to people.

And she stressed the need to test all vaccines on large numbers of people, of different ages and races, in the third phase of clinical trials, adding that the third phase trials are necessary to gain a high level of confidence that the vaccine protects against infection, and it also helps to get rid of side effects Rare that may not appear in a small group of healthy volunteers.

05 September 2020 – 17 Muharram 1442

12:26 PM


Does it give long immunity? .. “The Lancet” report answers

During the past hours, the “Lancet” medical journal published the results of the first and second phase of human trials of the Russian “Sputnik” vaccine; What helped identify a dangerous set of facts.

On August 11, the Al-Hurra channel said: Russian President Vladimir Putin announced that Moscow had succeeded in developing the first vaccine for the Corona virus, and that it had been approved for use.

The vaccine has been attacked and criticized strongly by scientists in various parts of the world, due to the fact that the vaccine did not pass all the required tests and was hasty to announce it. Human experiments were not completed until only two months before it was announced.

The report of the medical journal “The Lancet” revealed four facts, which the report focused on extracting from the results: Which:

* The idea of ​​a vaccine
The magazine confirmed that the vaccine depends on its idea on adenoviruses, which are the common cold viruses called Ad5 and Ad26, after they have become safe and unable to grow in the body, and which work to identify the body’s cells with the genetic code for the Corona virus proteins, called “spike protein.”

She added that when people are injected with these modified adenoviruses, the immune system is stimulated to recognize the Corona virus and respond to it, but it is not clear if the immunity lasts for years.

The magazine pointed out that the idea of ​​the vaccine used by the Russians is not new, and some other Corona vaccines that researchers are working on are used, including the Oxford University vaccine and the Ad26 vaccine developed by Johnson & Johnson.

Is it safe?
The Lancet stated that all adenovirus-based vaccines are safe, even at high doses; So Sputnik vaccine is safe for people between the ages of 18 – 60 years, but she wondered: Does it really protect against the Corona virus?

Does it give long immunity?
Russian experiments showed that the vaccine stimulates high levels of antibodies that can stick to the communication protein in the emerging virus, but the most important measure is the level of antibodies that work, and can the antibodies prevent or neutralize the virus? Which is not answered by the results.

The magazine indicated that the levels of antibodies are very low in this study, compared to trials of other published vaccines. So are the responses of T cells (the other arm of the immune system to fight the virus).

She emphasized that in the absence of international reference standards, it is not possible to know whether this vaccine is better or worse compared to the others.

The magazine added that it is difficult to determine if this level of neutralization for the virus provided by the vaccine is sufficient to protect against infection, and it is also difficult to determine how long these antibodies remain in the blood, as experiments show results after only one month.

Is it ready for general use?
The magazine stated that despite the positive results of a small trial of the first phase of the Sputnik vaccine, it must be tested on a much larger group of people before it is used and given to people.

And she stressed the need to test all vaccines on large numbers of people, of different ages and races, in the third phase of clinical trials, adding that the third phase trials are necessary to gain a high level of confidence that the vaccine protects against infection, and it also helps to get rid of side effects Rare that may not appear in a small group of healthy volunteers.





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