Disclosure of the results of proven drugs in the treatment of corona

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News Agent Since the emergence of the new epidemic of the Corona virus last December and its subsequent spread in large areas of the world, doctors in several countries starting with China, then the United States, Italy and France, have started testing drugs that are used for other purposes and are somewhat safe.

Some of these drugs have been certified to be tested through exceptional procedures, given the severe impact of the epidemic on humanity.

Now, just three months after the epidemic, the initial results of these drugs have begun to emerge, and three of them have been monitored, all with antiviral properties.
Chloroquine or hydroxychloroquine

He is 90 years old and used to treat malaria. In early March, French doctors in Marseille used this drug to treat 26 people with corona by giving them three doses per day, each amounting to 200 mg for ten days. Some people take doses with an antibiotic called Zithromax.

Six days after taking the medicine, it turned out that the amount of virus in the patients’ body was lower compared to those who did not take it.

The results of the study are not considered strong due to the small number of patients included in them, although there are reports of successful trials of chloroquine in China.

Anthony Fuchi, president of the National Institute of Allergy and Infectious Diseases in the United States, said scientists say there is “not enough evidence” for drug efficacy, in the absence of controlled clinical trials.

But in the absence of other options, New York State, which has become the global epicenter of the epidemic, decided to have 70,000 doses of hydroxychloroquine and 750,000 doses of chloroquine, in addition to azithromycin (also called zithromax).

His New York Governor said that his state “will start the experiments on Tuesday (…) There is a good basis for believing that the medicine is working. The President ordered the FDA to take action and moved.”
No one should take chloroquine without a prescription, as it may affect your heartbeat.

Favipiravir

News reports last week claimed that Chinese officials described this antiviral drug, made in Japan, as “clearly effective.”

Doctors in the Chinese province of Hubei tried it out of the outbreak in a group of 120 people with SK. Another similar group gave it to umifenovir (trade name Arbidol) which is an antibiotic used in Russia.

Doctors noted that fever and cough disappeared faster in the group that took faviravir, but a similar number of both groups had to undergo artificial respiration operations due to suffering from pneumonia.

Doctors favored faviravir over Arbidol.

Faviravir, known commercially in Japan as “Avigan”, prevents viruses from copying its genetic material and was discovered while searching for flu medications.
Lopinavir and Ritonavir

Doctors had to use these two drugs to treat HIV, in the hope of achieving rapid success in eliminating Corona.
A randomized study in January in China included 199 people, some of whom were given lopinavir and others ritonavir, twice a day for two weeks, while another group (the measurement group) received regular medical care.

Unfortunately, the results were not helpful, after 20 percent of patients died.
However, researchers in the United States are trying to find out whether a combination of the two drugs known as “calitra”, is working, especially for patients with less severe symptoms.

The main drug here is lopinavir, and it has proven effective in treating the Middle East respiratory syndrome (MERS) that appeared in Saudi Arabia in 2012, by disrupting the work of an important virus enzyme called protease.

Ritonavir works to increase the spread of the first drug in the body.

Source: Al-Hurra

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