The studies highlighted the importance of “microbiome”, which are the different types of bacteria that live in the intestine and affect many functions of the body and fight disease.
In the first study published on bioRxiv, the researchers reviewed the results of another 47 studies examining the associations between the genomes of the gut microbes and 13 common diseases, including schizophrenia, high blood pressure and asthma, all of which are considered “complex” diseases because they are caused by environmental and genetic factors, and then they compared These studies with 24 studies examine the relationship between genetic variants and diseases.
The scientists found that the genes in the gut microbes were better in identifying future diseases than the genetic variables of people by 20 percent, and the proportion reached 50 percent in the case of predicting colorectal cancer, but the genetic variables outperformed the “microbiome” in predicting diabetes from The first type.
Although study supervisor Braden Turney, from Harvard Medical School, acknowledged that the results of the study are still “preliminary,” he stressed that they may be beneficial in the future by using microbial and genetic traits together to improve patients’ lives.
Another study, published on MedRxiv, showed that the microbiome could predict death. It was based on another Finnish study that has tracked health data for thousands of participants since 1972.
The researchers found that individuals who had more Enterobacteriaceae and included Escherichia coli or “large germ bacteria” as well as “Salmonella” bacteria are 15 percent more likely to die during the next 15 years.
“I am optimistic and excited to get to a point where we can develop microbiome-based treatments and diagnoses,” said Samuel Minot, a microbiologist at the Fred Hutchinson Center for Cancer Research who was not involved in the research.
One of the advantages of a microbiome is that it is influenced by a person’s environment: “What he eats and the amount of exercise, for example, so it may be a better indication of diseases such as type 2 diabetes that tend to correlate with factors,” said researcher Gerwin Rees of the VIB-KU Leuven Center for Microbiology. Environmental person. ”